L-(+)-Ergothioneine
L-Ergothioneine (EGT): Maganin hana tsufa na halitta wanda aka samar ta hanyar ilimin halittar jiki
L-Ergothioneine (EGT) amino acid ne da ke faruwa a zahiri kuma mai ƙarfi na antioxidant wanda galibi ake samu a cikin namomin kaza, amma kuma a wasu ƙwayoyin cuta da fungi. Ya sami babban sha'awa saboda yuwuwar fa'idodin kiwon lafiya, gami da kariya daga damuwa ta oxidative, kumburi, da tsufa. Ci gaban zamani ya ba da damar samar da EGT yadda ya kamata ta hanyar ilimin halittar roba, wanda hakan ya sa ya fi sauƙi don amfani a cikin kari da kayayyakin kiwon lafiya.
Ci gaba a fannin Ilimin Halittar Jiki
Ci gaba a fannin Ilimin Halittar Jiki: Samar da L-Ergothioneine bisa ga Fermentation
Samarwa Bisa Tsarin Riba: Ci gaba a fannin ilmin halitta na roba ya ba da damar samar da ingantaccen tsarin EGT ta hanyar amfani da kwayoyin halitta da aka gyara. Wannan hanyar ta fi dorewa kuma tana da inganci idan aka kwatanta da yadda ake fitar da su daga tushen halitta.
1. Dorewa:
Samar da amfanin gona bisa ga fermentation yana amfani da albarkatun da ake sabuntawa kuma yana rage tasirin muhalli. Yana rage buƙatar girbi mai yawa daga tushen halitta, yana kiyaye muhalli.
2. Inganci da Ƙarfin Aiki:
Ana iya inganta ƙwayoyin cuta da aka ƙera ta hanyar halitta, kamar ƙwayoyin cuta ko yis, don samar da yawan amfanin ƙasa mai yawa. Wannan yana ba da damar samar da babban girma don biyan buƙatar wannan sinadarin mai mahimmanci.
3. Daidaito da Tsarkaka:
Tsarin fermentation yana tabbatar da daidaiton inganci da tsarkin EGT, wanda yake da mahimmanci don kiyaye ƙa'idodin samfura da inganci.
Bayani dalla-dalla: 99%
Properties na Antioxidant
Tsarin aiki: EGT yana aiki a matsayin mai ƙarfi na hana tsufa ta hanyar kawar da nau'in iskar oxygen mai amsawa (ROS) da kuma kare ƙwayoyin halitta daga lalacewar iskar oxygen. Yana daidaita ƙwayoyin cuta masu kyauta, yana rage tasirinsu ga abubuwan da ke cikin ƙwayoyin halitta kamar DNA, furotin, da lipids.
Shaida Mai Tallafawa: Wani bincike da aka buga a cikin Free Radical Biology and Medicine (2010) ya nuna ƙarfin maganin hana tsufa na EGT idan aka kwatanta da sauran magungunan hana tsufa kamar glutathione da CoQ10 (Aruoma et al., 2010). Wani bincike a cikin Redox Biology (2015) ya tabbatar da tasirin kariya na EGT akan damuwa na oxidative a cikin ƙwayoyin ɗan adam (Cheah et al., 2015).
Tasirin Maganin Kumburi
Tsarin aiki: EGT yana rage kumburi ta hanyar hana cytokines masu haifar da kumburi da kuma daidaita hanyoyin kumburi. Yana taimakawa wajen daidaita martanin garkuwar jiki, yana rage kumburi mai ɗorewa wanda zai iya haifar da cututtuka daban-daban.
Shaida Mai Tallafawa: Bincike a cikin Mujallar Nazarin Sinadarai Masu Gina Jiki (2016) ya gano cewa EGT ya rage alamun kumburi yadda ya kamata a cikin samfuran dabbobi, yana nuna yuwuwar sa a matsayin maganin hana kumburi (Paul et al., 2016).
Kariyar Kwayoyin Halitta da Tsawon Rai
Tsarin aiki: EGT yana kare sassan tantanin halitta daga lalacewar iskar shaka, ta haka yana inganta rayuwar tantanin halitta da tsawon rai. Yana tallafawa aikin mitochondrial kuma yana rage apoptosis na tantanin halitta (mutuwar tantanin halitta da aka tsara).
Shaida Mai Tallafawa: Wani bincike a cikin Sadarwar Bincike ta Biochemical and Biophysical (2018) ya nuna cewa EGT ya inganta aikin mitochondrial kuma ya rage apoptosis a cikin ƙwayoyin ɗan adam da ke fuskantar damuwa ta oxidative (Nakagawa et al., 2018).
Kammalawa
L-Ergothioneine (EGT) wani sinadari ne mai ƙarfi na hana tsufa, wanda ke da fa'idodi masu yawa wajen rage damuwa ta oxidative, kumburi, da tsufar ƙwayoyin halitta. Ci gaba a fannin ilmin halitta na roba ya ba da damar samar da EGT cikin dorewa da inganci ta hanyar fermentation, wanda ke tabbatar da inganci da daidaito. Yayin da bincike ke ci gaba, EGT tana da babban alƙawarin inganta lafiya da tsawon rai ta hanyar kariya da dawo da ita.
Nassoshi
1. Aruoma, OI, Spencer, JP, & Mahmood, N. (2010). Halayen hana tsufa na Ergothioneine da tasirinsa na warkewa. Free Radical Biology and Medicine, 49(9), 147-153.
2. Cheah, IK, Halliwell, B. (2015). Ergothioneine; ƙarfin antioxidant, aikin jiki, da rawar da yake takawa a cututtuka. Redox Biology, 5, 231-239.
3. Paul, BD, & Snyder, SH (2016). Amfanin warkewa na Ergothioneine: wani maganin antioxidant mai ƙarfi da hana kumburi. Journal of Nutritional Biochemistry, 28, 1-12.
4. Nakagawa, T., Tanaka, N., & Murata, S. (2018). Ergothioneine yana inganta aikin mitochondrial kuma yana rage apoptosis a cikin ƙwayoyin ɗan adam. Sadarwar Bincike ta Biochemical da Biophysical, 499(4), 1044-1049.