Tasirin Berberine Hydrochloride 7

Berberine hydrochloride Allunan da aka fi sani da "Huang Lian Su", magunguna ne na rage gudawa da ake sayarwa ba tare da takardar likita ba a China. Su babban alkaloid ne da ake samu a cikin rhizome na shukar Ranunculaceae. Coptis Chinensiskuma ana iya samunsa daga Barbary aristata, Phelodendron chinense, ko Gnaphalium affinisAllunan Berberine hydrochloride suna da aikace-aikace daban-daban na asibiti, waɗanda suka haɗa da waɗannan:

(A) Cututtukan Tsarin Narkewar Abinci

1. Cututtukan hanji: kamar su gastritis, gudawa, ciwon ciki, da sauransu.

Fassarar: Berberine hydrochloride yana da tasirin hana kamuwa da cuta iri-iri na Gram-positive da Gram-negative, musamman akan nau'ikan ƙwayoyin cuta daban-daban kamar su hemolytic streptococci da Staphylococcus aureus.

2. Ciwon cikiYana da tasirin hana kamuwa da cutar Helicobacter pylori, wanda zai iya rage gubar kamuwa da cutar Helicobacter pylori ga ƙwayoyin halitta, ta haka yana taimakawa wajen magance ciwon ciki.

Bayani: Tsarin aikin berberine hydrochloride Allunan magani wajen magance gyambon ciki sun haɗa da magungunan kashe ƙwayoyin cuta (anti-Helicobacter pylori), maganin kumburi, kariya daga mucosa na ciki, hana fitar da sinadarin acid na ciki, da kuma inganta aikin hanji. A asibiti, ana amfani da shi tare da wasu magunguna (kamar masu hana proton pump da maganin rigakafi) don inganta tasirin magani.

3. Ciwon cholecystitis na yau da kullun: Haɗa magani da allunan trisulfide don cholecystitis na yau da kullun ga tsofaffi na iya rage matakin abubuwan kumburi a cikin jinin majiyyaci da kuma inganta alamun asibiti.

Fassara: Nazarin asibiti ya nuna cewa haɗin berberine hydrochloride Allunan anethole da anethole trisulfide sun fi anethole trisulfide tasiri sosai wajen magance cutar cholecystitis mai tsanani a cikin tsofaffi. Alamomin marasa lafiya sun inganta sosai kuma matakan abubuwan da ke haifar da kumburi suna raguwa sosai.

4. Ciwon ulcerative colitis: Haɗa mesalazine ko sulfasalazine tare da wasu magunguna don magance ciwon ulcerative colitis na iya rage martanin kumburi sosai, inganta alamun asibiti, da kuma haɓaka murmurewa daga aikin shingen mucous na hanji.

Fassarar: Berberine hydrochloride Yana shiga tsakani wajen magance cututtukan ulcerative colitis ta hanyoyi da dama, kuma yana da tasirin hana kumburi, immunomodulatory da kuma kariya daga hanji, wanda hakan ya sanya shi magani mai kyau na maganin kari.

(B) Cututtukan da ke Kara narkewar abinci 

1. Ciwon sukari na nau'in 1 da na 2: Ana iya rage yawan sukari a jini ta hanyar amfani da shi shi kaɗai ko kuma a haɗa shi da magungunan Yamma (kamar metformin, glipizide, da sauransu).

Fassarar: Berberine hydrochloride Allunan suna taka muhimmiyar rawa wajen magance ciwon suga na nau'in 2 ta hanyoyi daban-daban, ciki har da inganta juriyar insulin, rage sukarin jini, daidaita kitsen jini, tasirin hana kumburi da hana tsufa, da kuma daidaita ƙwayoyin cuta na hanji. Ingancinsa tabbatacce ne, amincinsa yana da kyau, kuma ya dace musamman don dabarun maganin haɗin gwiwa.

2. Ciwon suga (hyperlipidemia)Yana iya daidaita sinadarin lipids na jini yadda ya kamata, rage yawan sinadarin cholesterol (TC) da triglycerides (TG) a cikin jini, da kuma ƙara yawan sinadarin lipoprotein mai yawa (HDL-C). Idan aka yi amfani da shi tare da statins (kamar atorvastatin da rosuvastatin), ana iya ƙara inganta tasirin rage kiba.

Fassara: Nazarin asibiti ya nuna cewa berberine na iya rage jimlar cholesterol, LDL cholesterol, da triglyceride, tare da raguwar har zuwa 20-50 mg/dL da 25-55 mg/dL, bi da bi. Saboda haka, berberine hydrochloride Allunan suna da kyakkyawan tasirin rage kiba kuma sun dace musamman ga marasa lafiya waɗanda ba za su iya jure wa statins ba.

3. Ciwon jijiyoyi na gefe na masu ciwon sukari: Yana hana kunna aldose reductase, yana rage tarin sorbitol, kuma yana kare aikin jijiyoyi.

Fassarar: Berberine hydrochloride yana inganta tsarin jijiyoyi da aikin cutar neuropathy ta gefen masu ciwon suga ta hanyar amfani da tsarin "anti-inflammatory + antioxidant + anti-apoptosis + metabolism regulatory", wanda ke da tushe na kimiyya da kuma damar asibiti a matsayin magani na gaba.