Nicotinamide Adenine Dinucleotide Hydrate
β-NADH, nau'in bitamin B3 (niacin) mai aiki a fannin ilmin halitta, muhimmin coenzyme ne a cikin tsarin samar da makamashin ƙwayoyin halitta na jiki. Yana taka muhimmiyar rawa a cikin sarkar jigilar lantarki ta mitochondrial, yana taimakawa wajen canza abubuwan gina jiki zuwa makamashi. Sau da yawa ana amfani da β-NADH a cikin kari don haɓaka kuzari, aikin fahimi, da kuma tallafawa lafiyar ƙwayoyin halitta gaba ɗaya.
Bayani dalla-dalla: 99%
Yana ƙara yawan samar da makamashin tantanin halitta: β-NADH yana ƙara yawan aikin mitochondrial, yana ƙara yawan samar da ATP (makamashi), wanda zai iya haifar da ingantaccen kuzarin jiki da na tunani »Birkmayer et al., 2009
Yana inganta aikin fahimta: Bincike ya nuna cewa β-NADH na iya tallafawa lafiyar kwakwalwa ta hanyar inganta fahimtar hankali, mayar da hankali, da ƙwaƙwalwa, musamman a cikin tsofaffi masu tsufa.
Yana tallafawa lafiyar zuciya da jijiyoyin jini: NADH tana da hannu wajen kiyaye lafiyar zuciya ta hanyar haɓaka amfani da makamashi mai inganci a cikin ƙwayoyin tsoka na zuciya" Ziegler et al., 2000.
Tasirin antioxidant: NADH yana taimakawa rage damuwa ta oxidative kuma yana iya kare ƙwayoyin halitta daga lalacewa da free radicals ke haifarwa, yana ba da gudummawa ga fa'idodin hana tsufa »Braidy et al., 2019
Tsarin aiki
β-NADH yana aiki a matsayin muhimmin coenzyme a cikin halayen redox a cikin sarkar jigilar lantarki ta mitochondrial. Yana ba da gudummawar electrons ga hadaddun I, yana sauƙaƙe samar da ATP, babban mai ɗaukar makamashi a cikin ƙwayoyin halitta. NADH kuma yana taka rawa wajen rage damuwa ta oxidative ta hanyar tasiri ga tsarin antioxidant, kamar sake samar da glutathione, wanda yake da mahimmanci don kare ƙwayoyin halitta daga lalacewa »Birkmayer et al., 2009】【Braidy et al., 2019】.
Nassoshi
Birkmayer, GD, da sauransu (1999). NADH yana inganta aikin fahimta a cikin marasa lafiya da cutar Alzheimer. Mujallar Watsa Jijiyoyi.
Birkmayer, JG (2009). NADH, Coenzyme Mai Ƙarfafawa: Bayani game da Matsayinsa a Aikin Kwayoyin Halitta da Amfani da Magunguna. Springer.
Ziegler, M., da sauransu (2000). Matsayin NADH a cikin Tsarin Metabolism na Makamashi da Lafiyar Zuciya. Bincike da Aiki a fannin Zuciya.
Braidy, N., da sauransu (2019). Tsarin metabolism na NAD+ a cikin cututtukan jijiyoyi da cututtukan mitochondrial. Neurochemistry International.